Issue 27
August 2001
The first National CRASH Trial Collaborators’ Meetings held in Spain and Switzerland

Seville, Spain

Angeles Muñoz and team from Trauma Centre 'Virgen del Rocio', Seville

The first Spanish CRASH Trial meeting was held in Seville on 18 May 2001, hosted by Angeles Muñoz, the National Co-ordinator.  The meeting which was held at the Seville Expo Centre was very well attended by doctors and nurses from many parts of Spain including: Almeria, Badajoz, Barcelona, Burgos, Cordoba, Cadiz, Granada, Malaga and Salamanca.  Already Dr Alvarez and Juan Nava from Hospital Mútua de Terrassa, Barcelona have ethical approval and are ready to start enrolling patients and many more centres are now seeking ethical approval.  Many thanks to CruzCampo brewery (the oldest in Spain!) who donated lunch to all the delegates.

The team at Trauma Centre 'Virgen Del Rocio' were among the first international hospitals to join the CRASH Trial and have already randomised 44 patients.

Zurich, Switzerland

Silke Ludwig and team in University Hospital of Zurich

The first Swiss CRASH Trial meeting was hosted by Silke Ludwig and Reto Stocker, in Zurich on 28 June 2001.  The meeting was held at the University Hospital of Zurich and was attended by doctors and nurses from Berne, Schaffhausen and Zurich.  Following the meeting Urs Denzler from Kantonsspital Schaffhausen very quickly obtained ethical approval and is now preparing to participate in the trial. 

Silke and Reto also joined the CRASH Trial early on in the start-up phase and have now enrolled 60 patients into the trial and get the gold star            for obtaining a follow-up rate of 100%!

Both meetings were a great success and we are delighted by the level of enthusiasm and commitment for the CRASH Trial in both these countries and worldwide.  The CRASH Trial is still well on target - but for it to succeed many more centres must join the already strong collaborative group and work together to answer the ‘corticosteroid in head injury’ question once and for all.  There is no time like the present - if you have not done so already, submit an application to your ethics committee and... 

Reminder to UK hospitals: 
NHS Number

It would help us enormously with the mammoth task of following up enrolled patients at six months if you were to enter the NHS number on the Early Outcome Form.  One of the follow-up strategies is to contact the Office for National Statistics for the patient's vital status and this job is made much easier and less costly for us if the NHS number is known.

Recruitment news
Every week more and more hospitals are joining the CRASH Trial.  The following have recently obtained ethical approval: Eros Bruzzone in Ospedale S Martino, Italy, Howard Brydon in North Staffordshire Royal Infirmary, UK and Nahit Cakar in Istambul Medical Faculty, TurkeyBill Bailey and team in Chesterfield and North Derbyshire Royal Hospital in the UK enrolled their first patient this month.  Congratulations!

.. Collaborating hospitals
A.Z. Kliena Hospital (Belgium)
Aberdeen Royal Infirmary (United Kingdom)
Angel Larralde Hospital (Venezuela)
Arrowe Park Hospital (United Kingdom)
Batticaloa General Hospital, Teaching (Sri Lanka)
Birmingham Heartlands Hospital (United Kingdom)
Blackburn Royal Infirmary (United Kingdom)
Bury General Hospital (United Kingdom)
Centre Hospitalier Regional de Namur (Belgium)
Centro Medico Dr. Rafael Guerra Mendez (Venezuela)
Chelsea and Westminster Hospital (United Kingdom)
Cheltenham General Hospital (United Kingdom)
Chesterfield & North Derbyshire Royal Hospital (United Kingdom)
City Hospital (United Kingdom)
Clinica Las Americas (Colombia)
Clinica Los Rosales S.A. (Colombia)
Colchester General Hospital (United Kingdom)
Countess of Chester Hospital (United Kingdom)
Doncaster Royal Infirmary (United Kingdom)
Dr. Enrique Tejera Hospital (Venezuela)
Dunedin Hospital (New Zealand)
Eastbourne District General Hospital (United Kingdom)
Ernst Moritz Arndt University (Germany)
Furness General Hospital (United Kingdom)
Harrogate District Hospital (United Kingdom)
Hope Hospital (United Kingdom)
Hospital Escuela (Argentina)
Hospital General de Medellin (Colombia)
Hospital General Regional Number 1 (Mexico)
Hospital Italiano (Argentina)
Hospital Municipal "Dr Leonidas Lucero" (Argentina)
Hospital Municipal Dr Hector J D'Agnillo (Argentina)
Hospital Mútua de Terrassa (Spain)
Hospital Nacional Profesor Alejandro Posadas 
Hospital of Jolimont (Belgium)
Hospital Pribram (Czech Republic)
Hospital San Bernardo (Argentina)
Hospital Universitario San Jorge (Colombia)
Hospital University Science Malaysia (Malaysia)
Hospital Zonal General de Agudos "Heroes de Malvinas" (Argentina)
IAMBE (Argentina)
Institute Of Neurology (United Kingdom)Instituto de Prevision Social (ITS) (Paraguay)
Istambul Medical Faculty (Turkey)
José Penna (Argentina)
KAT Hospital of Athens (Greece)
King George Hospital (United Kingdom)
Lagos University Teaching Hospital (Nigeria)
Lister Hospital (United Kingdom)
Masaryk Hospital (Czech Republic)
Mataria Teaching Hospital (Egypt)
Medway Maritime Hospital (United Kingdom)
Mobile ICU Centre Hospitalier Regional de Namur (Belgium)
Narh-Bita Hospital (Ghana)
National Hospital of Sri Lanka (Sri Lanka)
National Neuroscience Institute (Singapore)
Ninewells Hospital and Medical School (United Kingdom)
North Manchester General Hospital (United Kingdom)
North Staffordshire Royal Infirmary (United Kingdom)
Northern General Hospital (United Kingdom)
Ospedale S. Martino (Italy)
Princess Alexandra Hospital (United Kingdom)
Prof. Dr D Bagdasar Clinical Emergency Hospital (Romania)
Queen Elizabeth Hospital, Birmingham (United Kingdom)
Queen Elizabeth The Queen Mother Hospital (United Kingdom)
Reimann Hospital (Slovakia)
Research Institute for Special Surgery and Trauma (Czech Republic)
Royal Albert Edward Infirmary (United Kingdom)
Royal Bolton Hospital (United Kingdom)
Royal Liverpool University Hospital (United Kingdom)
Royal Oldham Hospital (United Kingdom)
Selly Oak Hospital (United Kingdom)
Spitalul Clinic De Urgenta Bucaresti (Romania)
St Helier Hospital (United Kingdom)
St James's University Hospital (Eire)
Stepping Hill Hospital (United Kingdom)
Suez Canal University (Egypt)
Trafford General Hospital (United Kingdom)
Trauma Centre - Virgen Del Rocio (Spain)
Tygerberg Academic Hospital (South Africa)
University Hospital Charles University (Czech Republic)
University Hospital of Zurich (Switzerland)
Univerzity Karlovy Neurochirurgicka Klinika (Czech Republic)
Wentworth Hospital (South Africa)
Whiston Hospital (United Kingdom)
Withybush General Hospital (United Kingdom)
Worthing Hospital (United Kingdom)

Nin Ritchie, MRC CRASH Trial Manager
CRASH Co-ordinating Centre, LSHTM, 49-51 Bedford Square, LONDON WC1B 3DP
Tel:+44(0)20 7299 4684    Fax:+44(0)20 7299 4663    email: